Frattini was part of the generation that made up the Italian design movement in the late 1950s through the 1960s. He was an architecture graduate of Milan Politecnico and became an industrial designer by default when he lacked appropriate lighting and furniture for his interiors. In 1956 he co-founded the ADI, Associazone per il Disegno Industriale. During his distinguished career, he collaborated with Gio Ponti, worked for Cassina and Acerbis, designed lamps for Artemide, was a board member of the Triennale di Milano and designed for Knoll. His work for Artemide resulted in the Boalum lamp together with Livio Castiglioni, and the Megaron lamp as well as several furniture collections for Cassina and exhibits for Ferrari.